This Thessaloniki hotel is located in the Ladadika area of town. The Plaza Art Hotel is 100 meters from the harbor and within five minutes' walk of the trade center. The sea front promenade and the ferry stops are near the hotel. The Plaza Art Hotel is less than 1 km from the main rail station and the port-side ferry docks. The airport is a 20 minute drive from the hotel

There are 35 rooms at the Plaza Art Hotel. The rooms are individually decorated, with original art on the walls and handmade rugs on the floors. Rooms have air conditioning, sound proofing, mini bars, direct dial telephones, Internet access, and en suite bathrooms. The suites have Jacuzzi tubs.

The Plaza Art Hotel is a contemporary boutique hotel done up in cream colors. It is seven levels high. There is a hot breakfast buffet offered each morning, and snacks are available throughout the day. The house restaurant offers traditionally inspired meals and seafood. Room service is available, as are lifts for access to the upper floors. Private parking spaces for hotel guests only are located near the hotel.